You lose the top 5.25" bay, use a single 120 rad (the PA160 is about as effective as a dual 120 rad) and mount it between the buttons and the PSU.
Phenom II 940 Black Edition quad core @ 3.5Ghz
2x1 gig OCZ PC26400 Platinum, 2x1gig GSkill PC26400
Some other stuff,
Even more stuff,
If the automobile had followed the same development cycle as the computer, a Rolls-Royce would today cost $100, get a million miles per gallon, and explode once a year, killing everyone inside. --Robert X. Cringely, InfoWorld magazine