Sandboxie and NOD32 is all you need.
Norton, McAffy and the others just slow a fast computer down to a crawl. Oh Yes they all work in protection, but just too much going on in the background.
Win7 64 bit
Intel i7 920 watercooled
Asus P6X580 Premium mobo,
GTX280 GPU watercooled
Synology NAS 207 Network Server with 2 Hitachi Terabite drives
LG NAS N2R1 with 2 ea 2 tb drives
LINKSYS PLK300 Powerline Network Kit