Adobe says you’ll have to upgrade to new versions of popular (and really expensive) software like Photoshop, InDesign and DreamWeaver if you want them to run well under Windows Vista. Current versions of many Adobe products won’t run flawlessly under Windows Vista, this announcement only confirms that they never will.
I’ve used Photoshop CS3 (beta) for a while under Vista and was not entirely impressed with it’s performance. I’m hoping that the retail version will at least have fixes to improve overall performance, or else people are not going to be pleased. With tools like Photoshop and InDesign, computers can get bogged down enough as is. This is one more reason to not upgrade to Vista, unless you are willing to take your chances.
Source: Download Squad