GREYCstoration is an open-source tool able to de-noise, inpaint, or resize 2D color images. This is a command-line program developed by the IMAGE team of the GREYC Lab in France and is available for Unix, Mac, and Windows systems under the CeCILL license. The algorithm is based on anisotropic diffusion partial differential equations. These equations are able to smooth an image while preserving its main structures.
If you don’t have Photoshop or some specialty tool, this is one you will want to add to your photo-editing arsenal. It’s command-line based, so you will have to get your hands a little dirty. I gave it a quick test though and actually found it to do a better job on my high-ISO night photos than Photoshop and Neat Image.
Source: Slashdot